epitope mapping within an internal region of ALG5 of human origin
Modification Notes
ALG5 (asparagine-linked glycosylation protein 5), also known as dolichyl-phosphate beta-glucosyltransferase, is a 324 amino acid protein belonging to the glycosyltransferase 2 family. Localized to the endoplasmic reticulum membrane, ALG5 is expressed widely in pancreas, placenta, liver, heart, brain, kidney, skeletal muscle and lung. Functionally, ALG5, in conjunction with ALG6, participates in the glucosylation of the oligomannose core in N-linked glycosylation of proteins. The addition of glucose residues to the oligomannose core is critical for optimal substrate recognition and, therefore, is necessary to ensure the efficient transfer of the oligomannose core to nascent glycoproteins. Multiple isoforms of ALG5 exist as a result of alternative splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of ALG5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of ALG5 of human origin
Tissue Specificity
epitope mapping within an internal region of ALG5 of human origin
Western blot analysis of ALG5 expression in Hep G2 whole cell lysate.
Application Notes
recommended for detection of ALG5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.