| Product Name | ATP5J Antibody (C-18) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the C-terminus of ATP5J of human origin |
| Modification Notes | Mitochondrial ATP synthase is composed of two multi-subunit complexes that utilize an inner membrane electrochemical gradient to catalyze the synthesis of ATP during oxidative phosphorylation. The two multi-subunit complexes are designated F1 and F0, the former of which comprises the soluble catalytic core and the latter of which comprises the membrane-spanning proton channel of ATP synthase. F1 consists of five distinct subunits, designated ATP5A, ATP5B, ATP5C1, ATP5D and ATP5E, while F0 consists of ten subunits, designated ATP5H, ATP5G1, ATP5I, ATP5G2, ATP5J2, ATP5J, ATP5G3, ATP5S, ATP5F1 and ATP5L. ATP5J, also known as ATP5A, ATPM, CF6 or F6, is a 108 amino acid protein that localizes to the mitochondrial membrane and exists as a subunit of the F0 complex. ATP5J is expressed as multiple alternatively spliced isoforms and is required for proper F1 and F0 interaction. Human ATP5J shares 73% sequence similarity with its rat counterpart, suggesting a conserved role between species. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of ATP5J of mouse and human origin by WB, IF and ELISA non cross-reactive with other ATP5 family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the C-terminus of ATP5J of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the C-terminus of ATP5J of human origin |
| Entrez Gene | 522 |
|---|
| Application Notes | recommended for detection of ATP5J of mouse and human origin by WB, IF and ELISA non cross-reactive with other ATP5 family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
