| Product Name | ZNF445 Antibody (S-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of ZNF445 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF445 (Zinc finger protein 445), also known as ZNF168 (Zinc finger protein 168) and ZKSCAN15 (Zinc finger protein with KRAB and SCAN domains 15), is a 1031 amino acid nuclear protein that contains one KRAB domain, one SCAN box domain and fourteen C2H2-type zinc fingers. ZNF445 is highly expressed in adult skeletal muscle and testis, while expressed at lower levels in small intestine, pancreas, colon, thymus, uterus and peripheral blood leukocytes. Overexpression of ZNF445 results in the activation of c-Jun and serum response element, suggesting a potential role in the MAPK signaling pathway. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of ZNF445 of human origin by WB, IF and ELISA non cross-reactive with other ZNF family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of ZNF445 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of ZNF445 of human origin |
| Entrez Gene | 353274 |
|---|
| Application Notes | recommended for detection of ZNF445 of human origin by WB, IF and ELISA non cross-reactive with other ZNF family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
