Application
Western blot analysis of hnRNP UL1 expression in non-transfected: (A) and mouse hnRNP UL1 transfected: (B) 293T whole cell lysates and Jurkat (C), Ramos (D) and K-562 (E) nuclear extracts.Application
Western blot analysis of hnRNP UL1 expression in non-transfected: (A) and human hnRNP UL1 transfected: (B) 293T whole cell lysates and Jurkat nuclear extract (C).Application
Western blot analysis of hnRP UL1 expression in Raji whole cell lysate.Application
Western blot analysis of hnRNP UL1 expression in 293T whole cell lysate (A) and HeLa nuclear extract (B).Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human muscle tissue showing nuclear staining.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing nuclear staining.| Product Name | hnRNP UL1 Antibody (G-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against hnRNP UL1 of human origin |
| Modification Notes | Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of polypeptides that contribute to mRNA transcription and pre-mRNA processing, as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP proteins, and their complexes are the major constituents of the spliceosome. The majority of hnRNP protein components are localized to the nucleus, however some shuttle between the nucleus and the cytoplasm. hnRNP UL1 (heterogeneous nuclear ribonucleoprotein U-like 1), also known as E1B-AP5 or HNRPUL1, is an 856 amino acid nuclear protein that functions as a transcriptional regulator, playing a role in mRNA processing and transport. Specifically, hnRNP UL1 binds to adenovirus E1B-55kDa oncoprotein and mediates nucleocytoplasmic RNA transport within E1B-55kDa-infected cells. hnRNP UL1 is expressed as five isoforms that are produced due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of hnRNP UL1 of human and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against hnRNP UL1 of human origin |
|---|---|
| Tissue Specificity | raised against hnRNP UL1 of human origin |
| Entrez Gene | 11100 |
|---|
Application
Western blot analysis of hnRNP UL1 expression in non-transfected: (A) and mouse hnRNP UL1 transfected: (B) 293T whole cell lysates and Jurkat (C), Ramos (D) and K-562 (E) nuclear extracts.
Application
Western blot analysis of hnRNP UL1 expression in non-transfected: (A) and human hnRNP UL1 transfected: (B) 293T whole cell lysates and Jurkat nuclear extract (C).
Application
Western blot analysis of hnRP UL1 expression in Raji whole cell lysate.
Application
Western blot analysis of hnRNP UL1 expression in 293T whole cell lysate (A) and HeLa nuclear extract (B).
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human muscle tissue showing nuclear staining.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing nuclear staining.| Application Notes | recommended for detection of hnRNP UL1 of human and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
