Application
Western blot analysis of PUS7L expression in non-transfected: (A) and human PUS7L transfected: (B) 293T whole cell lysates.Application
Western blot analysis of PUS7L expression in non-transfected: (A) and human PUS7L transfected: (B) 293T whole cell lysates.| Product Name | PUS7L Antibody (K-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of PUS7L of human origin |
| Modification Notes | PUS7L (pseudouridylate synthase 7 homolog (S. cerevisiae)-like) is a 701 amino acid protein that belongs to the pseudouridine synthase truD family and contains one TRUD domain. The PUS7L gene is conserved in chimpanzee, dog, cow, mouse, chicken and zebrafish, and maps to human chromosome 12q12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PUS7L of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with PUS7: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of PUS7L of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of PUS7L of human origin |
| Entrez Gene | 83448 |
|---|
Application
Western blot analysis of PUS7L expression in non-transfected: (A) and human PUS7L transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of PUS7L expression in non-transfected: (A) and human PUS7L transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of PUS7L of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with PUS7: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
