Application
Western blot analysis of NHN1 expression in non-transfected: (A) and human NHN1 transfected: (B) 293T whole cell lysates.| Product Name | NHN1 Antibody (V-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of NHN1 of human origin |
| Modification Notes | NHN1, also known as ZC3H18 (zinc finger CCCH domain-containing protein 18), is a 953 amino acid nuclear protein that contains one C3H1-type zinc finger and exists as two alternatively spliced isoforms. The gene that encodes NHN1 contains more than 61,500 bases and maps to human chromosome 16q24.2. Encoding over 900 genes and consisting of approximately 90 million base pairs, chromosome 16 makes up nearly 3% of the human genome and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, when mutated, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. Alterations in the CREB gene and NOD2 gene, both of which are located on chromosome 16, results in Rubinstein-Taybi syndrome and Crohn's disease, respectively. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NHN1 of mouse and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of NHN1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of NHN1 of human origin |
| Entrez Gene | 124245 |
|---|
Application
Western blot analysis of NHN1 expression in non-transfected: (A) and human NHN1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of NHN1 of mouse and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
