epitope corresponding to amino acids 415-479 mapping within an internal region of PHACTR4 of human origin
Modification Notes
Phosphatase and actin regulator (PHACTR) family of proteins play a key role in inhibiting the activity of a multifunctional enzyme, protein phosphatase 1 (PP1). PP1 promotes synaptic activity and dendritic morphology in the nervous system. It is suggested that members of the PHACTR family members may be involved in regulation of cytoskeletal dynamics due to their interaction with cytoplasmic ∫-actin and globular Actin (G-actin). PHACTR4 (Phosphatase and actin regulator 4), also known as PRO2963, is a 702 amino acid protein that regulates neural tube and optic fissure closure. PHACTR4 contains three RPEL motifs and multiple phosphorylation sites. Six isoforms exist due to alternative splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of PHACTR4 of mouse and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 415-479 mapping within an internal region of PHACTR4 of human origin
Tissue Specificity
epitope corresponding to amino acids 415-479 mapping within an internal region of PHACTR4 of human origin