Application
Western blot analysis of LYSMD3 expression in non-transfected: (A) and mouse LYSMD3 transfected: (B) 293T whole cell lysates.| Product Name | LYSMD3 Antibody (N-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of LYSMD3 of human origin |
| Modification Notes | LYSMD3 (LysM and putative peptidoglycan-binding domain-containing protein 3) is a 306 amino acid single-pass membrane protein that contains one LysM repeat and exists as three alternatively spliced isoforms. The gene encoding LYSMD3 maps to human chromosome 5q14.3. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LYSMD3 isoforms 1-3 of human origin by WB, IP, IF and ELISA non cross-reactive with other LYSMD family members also reactive with additional species, including canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of LYSMD3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of LYSMD3 of human origin |
| Entrez Gene | 116068 |
|---|
Application
Western blot analysis of LYSMD3 expression in non-transfected: (A) and mouse LYSMD3 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of LYSMD3 isoforms 1-3 of human origin by WB, IP, IF and ELISA non cross-reactive with other LYSMD family members also reactive with additional species, including canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
