epitope corresponding to amino acids 150-241 mapping at the C-terminus of TSPAN1 of human origin
Modification Notes
Tetraspanins are a group of hydrophobic membrane proteins that interact with a wide variety of proteins including intracellular signaling molecules, integrins and membrane receptors. Members of the tetraspanin family are characterized by the presence of four hydrophobic domains and play a role in cell development, activation, growth and motility. TSPAN1 (tetraspanin 1), also known as NET1, TM4C or TM4SF, is a 241 amino acid multi-pass membrane protein that localizes to the lysosome membrane. Overexpressed in many human cancers, TSPAN1 is suggested to play an important role in colon cancer progression and in gastric cancer cell migration and invasion. TSPAN1 may also be an important breast cancer suppressor gene. The gene encoding TSPAN1 is located on human chromosome 1p34.1. Chromosome 1 spans about 260 million base pairs, makes up 8% of the human genome and contains approximately 3,000 genes
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of TSPAN1 of human origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 150-241 mapping at the C-terminus of TSPAN1 of human origin
Tissue Specificity
epitope corresponding to amino acids 150-241 mapping at the C-terminus of TSPAN1 of human origin