Application
Western blot analysis of HKR1 expression in non-transfected: (A) and human HKR1 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of HKR1 expression in 293T (A) and HeLa (B) whole cell lysates and HeLa nuclear extract (C).| Product Name | HKR1 Antibody (S-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of HKR1 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HKR1, also known as Krüppel-related zinc finger protein 1 or zinc finger protein 875, is a 659 amino acid nuclear protein that is thought to play a role in transcriptional regulation. Existing as two alternatively spliced isoforms, HKR1 is a member of the Krüppel C2H2-type zinc-finger protein family and contains thirteen C2H2-type zinc fingers and one KRAB domain. The gene encoding HKR1 maps to human chromosome 19q13.12. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of HKR1 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of HKR1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of HKR1 of human origin |
| Entrez Gene | 284459 |
|---|
Application
Western blot analysis of HKR1 expression in non-transfected: (A) and human HKR1 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of HKR1 expression in 293T (A) and HeLa (B) whole cell lysates and HeLa nuclear extract (C).| Application Notes | recommended for detection of HKR1 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
