Application
Western blot analysis of CYP4X1 expression in non-transfected: (A) and human CYP4X1 transfected: (B) 293T whole cell lysates.| Product Name | CYP4X1 Antibody (H-90) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events). CYP4X1 (cytochrome P450, family 4, subfamily X, polypeptide 1) is a 509 amino acid peripheral membrane protein of the microsome and endoplasmic reticulum. Expressed in brain, aorta and trachea, CYP4X1 may play a role in neurovascular function and is encoded by a gene that maps to human chromosome 1p33. Chromosome 1 spans 260 million base pairs, contains over 3,000 genes, and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease and Gaucher disease. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CYP4X1 of human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 196-285 mapping within an internal region of CYP4X1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 196-285 mapping within an internal region of CYP4X1 of human origin |
Application
Western blot analysis of CYP4X1 expression in non-transfected: (A) and human CYP4X1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of CYP4X1 of human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
