Monoacylglycerol O-acyltransferase (MGAT) catalyzes diacylglycerol (a precursor to triacylglycerol) synthesis. MGAT is important in intestinal absorption of dietary fat because resynthesis of triacylglycerol is needed for the assembly of the lipoproteins that transport absorbed fat to tissues. MGAT1 is expressed in stomach, kidney, liver and adipose tissue but is not found in the intestine. On the contrary, MGAT2 (monoacylglycerol O-acyltransferase 2) is highly expressed in the small intestine as well as in kidney, liver, colon, stomach and white adipose tissue. MGAT 3 (monoacylglycerol O-acyltransferase 3) is highly homologous to MGAT1 and MGAT2. The expression of MGAT3 is restricted to the gastrointestinal tract, most concentrated in the ileum.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of MGAT2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including porcine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 121-200 mapping within an internal region of MGAT2 of human origin
Tissue Specificity
epitope corresponding to amino acids 121-200 mapping within an internal region of MGAT2 of human origin