Application
Western blot analysis of SH3TC1 expression in mouse thymus tissue extract.| Product Name | SH3TC1 Antibody (L-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the C-terminus of SH3TC1 of human origin |
| Modification Notes | SH3TC1 (SH3 domain and tetratricopeptide repeats-containing protein 1) is a 1,336 amino acid protein containing one src-homology 3 (SH3) domain and nine tetratricopeptide (TPR) repeats. SH3 domains bind to proline-rich peptides, and tertiary interactions involving loops on the SH3 domain lead to increased binding affinity and specificity. TPR domains play an important role in protein-protein interactions. The gene encoding SH3TC1 maps to human chromosome 4, which houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SH3TC1 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with SH3TC2 also reactive with additional species, including equine, canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of SH3TC1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of SH3TC1 of human origin |
| Entrez Gene | 54436 |
|---|
Application
Western blot analysis of SH3TC1 expression in mouse thymus tissue extract.| Application Notes | recommended for detection of SH3TC1 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with SH3TC2 also reactive with additional species, including equine, canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
