epitope mapping near the C-terminus of SLC10A3 of human origin
Modification Notes
The SLC10 family of sodium/bile salt cotransporters contains over 50 members in animal, plant and bacterial species. SLC10A3 (solute carrier family 10 (sodium/bile acid cotransporter family), member 3), also known as P3 or DXS253E, is a 477 amino acid multi-pass membrane protein belonging to the sodium:bile acid symporter family. A few members of the sodium:bile acid symporter family, such as NTCP (also known as SLC10A1) and Asbt (also known as SLC10A2), are involved in maintaining enterohepatic circulation of bile acids by mediating the first step of active bile transport through membrane barriers of liver and intestine. Other family members, including SLC10A6, play an important role in the cellular delivery of specific prohormones in testis, placenta, adrenal gland and other peripheral tissues. Family members such as SLC10A3 are uncharacterized and their functions are unknown. SLC10A3 is encoded by a gene located on human chromosome Xq28.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of SLC10A3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other SLC10A family members also reactive with additional species, including canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping near the C-terminus of SLC10A3 of human origin
Tissue Specificity
epitope mapping near the C-terminus of SLC10A3 of human origin
Western blot analysis of SLC10A3 expression in mouse liver tissue extract (A) and RAW 264.7 (B) and C2C12 (C) whole cell lysates.
Application Notes
recommended for detection of SLC10A3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other SLC10A family members also reactive with additional species, including canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.