Application
Immunofluorescence staining of formalin-fixed Hep G2 cells showing nuclear and cytoplasmic localization.| Product Name | ANKRD2 Antibody (D-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD2 (ankyrin repeat domain 2), also known as ARPP or skeletal muscle ankyrin repeat protein, is a 360 amino acid protein involved in skeletal muscle hypertrophy that is expressed in slow fibers of skeletal and cardiac muscles and found in kidney, to a lesser extent. ANKRD2 is a member of the conserved muscle ankyrin repeat protein (MARP) family, whose expression can be triggered by injury, hypertrophy or physiological stress. Expressed as two alternatively spliced isoforms, ANKRD2 contains five ANK repeats and is encoded by a gene that maps to human chromosome 10q24.1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of ANKRD2 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other ANKRD family members also reactive with additional species, including equine, canine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of ANKRD2 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of ANKRD2 of human origin |
| Entrez Gene | 26287 |
|---|
Application
Immunofluorescence staining of formalin-fixed Hep G2 cells showing nuclear and cytoplasmic localization.| Application Notes | recommended for detection of ANKRD2 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other ANKRD family members also reactive with additional species, including equine, canine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
