| Product Name | MAGP-1 Antibody (H-105) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Elastic fibers endow loose connective tissue with a resilience that complements the tensile strength of collagenous fibers. They are composed of the protein elastin and a network of 10-12 nm microfibrils, which contain several glycoproteins, including fibrillin-1, fibrillin-2, and the microfibril-associated glycoproteins MAGP-1 and MAGP-2. During elastogenesis, MAGP-1 and MAGP-2 bind the fibrillins to tropoelastin in the extracellular matrix of several elastic and non-elastic tissues. MAGP-1 is an O-Glycosylated protein secreted to the extracellular space and the extracellular matrix. MAGP-1 associates with Biglycan and elastin in a ternary complex. It can make intermolecular disulfide bonds with other MAGP-1 molecules or with other microfibril components and may form transglutaminase cross-links. Underexpression and overexpression of the Zebrafish homolog of MAGP-1 (Magp-1) protein levels demonstrate the critical role of MAGP-1 in vascular development. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of MAGP-1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-105 mapping at the N-terminus of MAGP-1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-105 mapping at the N-terminus of MAGP-1 of human origin |
| Entrez Gene | 4237 |
|---|
| Application Notes | recommended for detection of MAGP-1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
