| Product Name | LTB4R2 Antibody (H-86) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The P2Y receptor family consists of G-protein coupled receptors, which mediate the effects of extracellular nucleotides, primarily through the activation of phospholipase C. The P2Y receptors are important in the activation of leukocytes and platelets in response to inflammation or vascular damage. Leukotriene B4 receptor 1 (LTB4-R1), also designated P2Y purinoceptor 7, is a receptor for extracellular ATP, UTP and ADP. Through modulation of L-type calcium currents, LTB4-R1 is involved in the regulation of cardiac muscle contraction. It is also a receptor for leukotriene B4 (LTB4), a potent chemoattractant involved in inflammation and immumne response. Leukotriene B4 receptor 2 (LTB4R2) is a ubiquitously expressed 358-amino acid receptor for LTB4. It is an integral membrane protein acting as a receptor for leukotrienes, is widely expressed and mediates chemotaxis of macrophages and granulocytes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LTB4R2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 141-220 mapping within an internal region of LTB4R2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 141-220 mapping within an internal region of LTB4R2 of human origin |
| Entrez Gene | 56413 |
|---|
| Application Notes | recommended for detection of LTB4R2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
