| Product Name | BVES Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Blood vessel epicardial substance (BVES), also designated Popeye protein 1, is a transmembrane protein that plays a role in cell-cell interactions and adhesion, specifically at tight junctions. BVES is composed of an extracellular amino-terminus, three transmembrane domains and a cytoplasmic carboxyl-terminus. It is expressed in the developing coronary vascular system, specifically in the proepicardium, migrating epithelial epicardium, delaminated vasculogenic mesenchyme and vascular smooth muscle cells, where it functions to direct development in heart, epithelial and muscle cells during embryogenesis. BVES accumulates at points of cell-cell contact, such as filopodia and cell borders, and promotes adhesion prior to the arrival of E-cadherin. It also regulates epithelial integrity during cell movement and growth. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of BVES of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of BVES of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of BVES of human origin |
| Entrez Gene | 11149 |
|---|
| Application Notes | recommended for detection of BVES of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
