| Product Name | Sec24D Antibody (H-155) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Sec24D (Sec24-related protein D) is ubiquitously expressed but exhibits predominant expression in heart, placenta, liver and pancreas. Sec24D belongs to the Sec24 subfamily of the Sec23/Sec24 family of proteins. Members of this family participate in vesicle trafficking from the endoplasmic reticulum (ER) to the Golgi apparatus. Sec24D is one of four mammalian proteins, namely Sec24A, Sec24B, Sec24C and Sec24D, that are highly related to the Saccharomyces cerevisiae protein Sec24, a component of the coat protein complex COPII that mediates the selective export of membrane proteins from the ER. Similar to its yeast counterpart, Sec24D functions as a component of the cytoplasmic COPII complex. The COPII complex acts as a coat, covering ER-derived transport vesicles and promoting the transport of secretory proteins to the Golgi apparatus. Sec24D shares 50% amino acid identity with the ubiquitously expressed Sec24C protein. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Sec24D of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 846-1000 mapping near the C-terminus of Sec24D of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 846-1000 mapping near the C-terminus of Sec24D of human origin |
| Entrez Gene | 9871 |
|---|
| Application Notes | recommended for detection of Sec24D of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
