NUBP2 (nucleotide binding protein 2), also known as cytosolic Fe/S cluster assembly factor NUBP2, is a 271 amino acid protein and component of cytosolic iron-sulfur (Fe/S) protein assembly machinery. Localizing to both nucleus and cytoplasm, NUBP2 is found at centrosomes during mitosis and is widely expressed, with highest levels of expression in skeletal muscle and fetal liver, lung, brain and kidney. NUBP2 is essential for extramitochondrial Fe/S protein maturation and is thought to transfer a labile 4Fe-4S cluster to various apoproteins. NUBP2 is a member of the NUBP/MRP gene subfamily of ATP-binding proteins and is encoded by a gene that maps to human chromosome 16p13.3 and mouse chromosome 17 A3.3.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of NUBP2 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA non cross-reactive with NUBP1 or NUBPL
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 195-275 mapping at the C-terminus of NUBP2 of mouse origin
Tissue Specificity
epitope corresponding to amino acids 195-275 mapping at the C-terminus of NUBP2 of mouse origin