| Modification Notes |
Sec6 is one of eight protein subunits composing the mammalian exocyst complex (Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70, and Exo84). The mammalian exocyst complex (sec 6/8) is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Sec6/8 regulates polarized secretion in a GTP-dependent manner. Human Sec6 maps to chromosome 5p15.33. |