Application
Western blot analysis of CYP2W1 expression in non-transfected 293: (A), human CYP2W1 transfected 293: (B) and Hep G2 (C) whole cell lysates.| Product Name | CYP2W1 Antibody (H-175) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. There are currently 57 known active cytochrome P450 (CYP) genes and 58 known pseudogenes present in the human genome. Several P450 enzymes have been classified by sequence similarities as members of the CYP1A and CYP2A subfamilies. CYP2W1 is a 490 amino acid protein that belongs to the CYP2 family of cytochrome P450 proteins. These proteins are usually involved in the metabolism of foreign compounds. CYP2W1 metabolizes arachidonic acid and catalyzes the oxidation of indole. CP2W1 represents a tumor-specific P450 isoform that is universally conserved in vertebrates and is a potential drug target in cancer therapeutics. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CYP2W1 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 121-295 mapping within an internal region of CYP2W1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 121-295 mapping within an internal region of CYP2W1 of human origin |
| Entrez Gene | 54905 |
|---|
Application
Western blot analysis of CYP2W1 expression in non-transfected 293: (A), human CYP2W1 transfected 293: (B) and Hep G2 (C) whole cell lysates.| Application Notes | recommended for detection of CYP2W1 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
