| Product Name | CD37 Antibody (H-100) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Tetra-spans transmembrane family (TSTF) members (CD9, CD37, CD53, CD63, CD81 and CD82) are cell-surface proteins that are characterized by the presence of four hydrophobic, membrane-spanning domains (1,2). TSTF members can mediate signal transduction events influencing the regulation of cell development, adhesion, activation, growth and motility (2,3). The human CD37 gene maps to chromosome 19p13-q13.4 and encodes a 281 amino acid protein (2). CD37 is a cell surface glycoprotein that can complex with integrins and other TSTF proteins and may play a role in T-cell-B-cell interactions (2,4). CD37 is strongly expressed on normal and neoplastic mature sIg+ B cells and is detected at low levels on resting and activated T cells, neutrophils, granulocytes and monocytes (2,4,5). Transgenic mouse models elicit no changes in development and cellular composition of lymphoid organs where CD37 is lacking (4). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CD37 of mouse, rat and human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 182-281 mapping at the C-terminus of CD37 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 182-281 mapping at the C-terminus of CD37 of human origin |
| Entrez Gene | 951 |
|---|
| Application Notes | recommended for detection of CD37 of mouse, rat and human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
