| Product Name | Peroxin 10 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Peroxisomes are single-membrane bound organelles present in virtually all eukaryotic cells. They are involved in numerous catabolic and anabolic pathways, including beta-oxidation of very long chain fatty acids, metabolism of hydrogen peroxide, plasmalogen biosynthesis and bile acid synthesis. The Peroxin gene family, which includes more than 20 members, is required for peroxisome biogenesis. Peroxin 10 (Peroxisome biogenesis factor 10), also known as RNF69 (RING finger protein 69), is a 326 amino acid protein that exhibits E3 ligase activity in vitro, suggesting that it is involved in Ubc4-dependent ubiquination. Defects in the gene encoding Peroxin 10 are the result of a number of different disorders, such as Peroxisome biogenesis disorder complementation group 7, Zellweger syndrome and adrenoleukodystrophy neonatal. There are two isoforms of Peroxin 10 that are produced as a result of alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Peroxin 10 of mouse, rat and human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 33-326 mapping at the C-terminus of Peroxin 10 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 33-326 mapping at the C-terminus of Peroxin 10 of human origin |
| Entrez Gene | 5192 |
|---|
| Application Notes | recommended for detection of Peroxin 10 of mouse, rat and human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
