Pericentrin 1 (also designated Frount protein or Nucleoporin Nup75) is an integral anchor protein which has cytoskeletal anchoring activity. It is a highly conserved centrosome protein involved in microtubule organization and is also active in centrosome assembly by binding dynein complexes. Pericentrin acts as a regulator of microtubule nucleation by associating with gamma-tubulin and anchors the PKA holoenzyme at the association site. The gene encoding human pericentrin 1 maps to chromosome 17q25.2.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Pericentrin 1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-300 mapping at the N-terminus of Pericentrin 1 of human origin
Tissue Specificity
epitope corresponding to amino acids 1-300 mapping at the N-terminus of Pericentrin 1 of human origin
recommended for detection of Pericentrin 1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.