Application
Western blot analysis of TFPI-2 expression in KNRK whole cell lysate (A) and rat placenta tissue extract (B).Application
Western blot analysis of TFPI-2 expression in MCF7 whole cell lysate.Application
Western blot analysis of TFPI-2 expression in JAR whole cell lysate.Application
Western blot analysis of TFPI-2 expression in non-transfected: (A) and mouse TFPI-2 transfected: (B) 293T whole cell lysates.| Product Name | TFPI-2 Antibody (M-110) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The extrinsic pathway of blood coagulation is initiated by contact of plasma Factor VII with tissue factor, a cellular membrane glycoprotein that normally is segregated from the bloodstream but can be exposed after tissue injury or newly synthesized in endothelial cells or leukocytes after stimulation by endotoxin and cytokines. Inhibition of Factor VIIA tissue factor activity requires a plasma component (tissue factor pathway inhibitor (TFPI), lipoprotein-associated coagulation inhibitor (LACI) or extrinsic pathway inhibitor (EPI)) and Factor XA. TFPI directly inhibits Factor XA, and, in an XA-dependent fashion, also inhibits the Factor VIIA tissue factor catalytic complex. TFPI is a multivalent, Kunitz-type proteinase inhibitor that circulates in association with plasma lipoproteins VLDL, LDL and HDL. TFPI-2 (also known as placental protein 5) is a related glycoprotein that was originally isolated from human placenta. The genes which encode for TFPI and TFPI-2 map to human chromosomes 2q31-q32.1 and 7q22, respectively. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TFPI-2 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 71-180 mapping within an internal region of TFPI-2 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 71-180 mapping within an internal region of TFPI-2 of mouse origin |
| Entrez Gene | 7980 |
|---|
Application
Western blot analysis of TFPI-2 expression in KNRK whole cell lysate (A) and rat placenta tissue extract (B).
Application
Western blot analysis of TFPI-2 expression in MCF7 whole cell lysate.
Application
Western blot analysis of TFPI-2 expression in JAR whole cell lysate.
Application
Western blot analysis of TFPI-2 expression in non-transfected: (A) and mouse TFPI-2 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of TFPI-2 of mouse, rat and, to a lesser extent, human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
