Application
Western blot analysis of LHX6 expression in NIH/3T3 (A) and RAW 264.7 (B) whole cell lysates.| Product Name | LHX6 Antibody (H-75) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | During development, genetically distinct subtypes of motor neurons express unique combinations of LIM-type homeodomain factors, which regulate cell migration and guide motor axons to establish the fidelity of a binary choice in axonal trajectory. The LIM gene family encodes a set of proteins which carry the LIM domain, a unique cysteine-rich zinc-binding motif. LHX6 (LIM homeobox 6), also known as LHX6.1, is a 363 amino acid nuclear protein that contains two LIM zinc-binding domains and one homeobox DNA-binding domain. Expressed specifically in brain, LHX6 is thought to function as a transcriptional regulator that may play a role in the development and differentiation of lymphoid and neural cells. Additionally, LHX6 is hypermethylated in head and neck carcinomas and may be a novel tumor marker. Two isoforms of LHX6, designated LHX6.1A and LHX6.1B, exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LHX6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-75 mapping at the N-terminus of LHX6 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-75 mapping at the N-terminus of LHX6 of human origin |
| Entrez Gene | 26468 |
|---|
Application
Western blot analysis of LHX6 expression in NIH/3T3 (A) and RAW 264.7 (B) whole cell lysates.| Application Notes | recommended for detection of LHX6 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
