Application
Western blot analysis of BMP-9 expression in mouse liver tissue extract.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human hepatocarcinoma tissue showing cytoplasmic localization.| Product Name | BMP-9 Antibody (G-23) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Bone morphogenic protein-9 (BMP-9), like other members of the TGF beta growth factor superfamily, plays an important role in tissue morphogenesis, particularly in bone and connective tissue. Additionally, liver cells such as HepG2 express receptors to BMP-9, through which it stimulates cell proliferation and regulates blood glucose concentration, an effect not observed in treatment with TGF-beta. These in vivo activities appear to be exploitable in novel therapies; research shows that addition of BMP-9 or BMP-9 encoding adenoviral vectors promote bone formation ex vivo and in immune deficient animals. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of BMP-9 of mouse and human origin by WB IP IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of BMP-9 of mouse and human origin by WB, IP, IF, IHC(P) and ELISA |
| Entrez Gene | 2658 |
|---|
Application
Western blot analysis of BMP-9 expression in mouse liver tissue extract.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human hepatocarcinoma tissue showing cytoplasmic localization.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
