Application
Western blot analysis of STAC expression in non-transfected 293T: (A), human STAC transfected 293T: (B) and A-431 (C) whole cell lysates.| Product Name | STAC Antibody (S-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | STAC (SH3 and cysteine rich domain-containing protein), also known as STAC1, is a 402 amino acid protein that contains one SH3 (Src homology 3) domain and one cysteine-rich domain (CRD). Expressed in brain, STAC is a neuron-specific protein that localizes to the cytoplasm and, based on the frequent involvement of SH3 and CRD domains in signal transduction, is believed to play a role in neuron-specific signal transduction. In addition, STAC may be involved in protecting cells from apoptosis. Due to its neuron-specific expression and putative role in signal transduction, STAC may be implicated in a variety of hereditary neurological diseases. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of STAC of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with family members STAC2 or STAC3 also reactive with additional species, including bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of STAC of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of STAC of human origin |
| Entrez Gene | 6769 |
|---|
Application
Western blot analysis of STAC expression in non-transfected 293T: (A), human STAC transfected 293T: (B) and A-431 (C) whole cell lysates.| Application Notes | recommended for detection of STAC of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with family members STAC2 or STAC3 also reactive with additional species, including bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
