Application
Western blot analysis of Taspase 1 expression in mouse kidney tissue extract.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human colon carcinoma tissue showing cytoplasmic localization.| Product Name | Taspase 1 Antibody (A-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of Taspase 1 of mouse and human origin by WB, IP, IF, IHC(P), ELISA |
| Modification Notes | Taspase 1, also known as TASP1 or C20orf13, is a 420 amino acid endopeptidase which cleaves specific substrates following aspartate residues and is required for MLL (myeloid/lymphoid or mixed-lineage leukemia ) processing and, ultimately, correct expression of the Hox A gene cluster. After translation, Taspase 1 is subject to autoproteolytic processing which results in the creation of two subunits, designated alpha and beta, which reassemble into a multimeric structure and are required for proper Taspase 1 activity. The gene encoding Taspase 1 maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of Taspase 1 of mouse and human origin by WB IP IF IHC(P) ELISA |
|---|---|
| Tissue Specificity | recommended for detection of Taspase 1 of mouse and human origin by WB, IP, IF, IHC(P), ELISA |
| Entrez Gene | 55617 |
|---|
Application
Western blot analysis of Taspase 1 expression in mouse kidney tissue extract.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human colon carcinoma tissue showing cytoplasmic localization.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
