SFI1, also known as PISD, is a 1242 amino acid protein belonging to the SFI1 family. Subcellularly localized to the centrosome, SFI1 interacts with Centrin-2 via a conserved Trp residue in the C-terminal end of SFI1. Via this interaction with Centrin-2, SFI1 plays a role in the dynamic structure of centrosome-associated contractile fibers. SFI1 also contains six HAT repeats, which may be involved in protein-protein interactions. SFI1 is expressed as seven isoforms produced by alternative splicing. SFI1 has been found to be expressed in brain, testis, uterus and lung.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of SFI1 of human origin by WB, IP, IF and ELISA
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping near the C-terminus of SFI1 of human origin
Tissue Specificity
epitope mapping near the C-terminus of SFI1 of human origin