Application
Western blot analysis of Rab GDI β expression in Hep G2 whole cell lysate.| Product Name | Rab GDI β Antibody (P-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of Rab GDI β of human origin by WB, IP and ELISA; also reactive with additional species, including canine |
| Modification Notes | Rab proteins, a family of Ras-related small GTP-binding proteins, play a key role in regulating intracellular vesicle trafficking. Rab GDP dissociation inhibitor (Rab GDI or GDI2) forms a soluble complex with Rab proteins and thereby prevents the exchange of GDP for GTP. In mammals, there exist two major isoforms, Rab GDI å, also known as XAP-4, and Rab GDI ∫. While the mammalian Rab GDI ∫-genes are ubiquitously expressed, the Rab GDI å genes are predominantly brain-specific. Since it is expressed predominantly in neural and sensory tissues, Rab GDI å may serve a specific function in neural signal transmission. The gene sequences for the Rab GDI proteins are extremely conserved in evolution, with substantial homology preserved across three eukaryotic kingdoms. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of Rab GDI &beta of human origin by WB IP and ELISA also reactive with additional species including canine |
|---|---|
| Tissue Specificity | recommended for detection of Rab GDI β of human origin by WB, IP and ELISA; also reactive with additional species, including canine |
| Entrez Gene | 2665 |
|---|
Application
Western blot analysis of Rab GDI β expression in Hep G2 whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
