recommended for detection of PCBP4 of mouse, rat and human origin by WB, IP and ELISA; also reactive with additional species, including canine
Modification Notes
Poly(rC)-binding protein 4 (PCBP4), also known as AlphaCP4, is a 403 amino acid protein belonging to the AlphaCP subfamily. AlphaCP proteins bind to RNA at specific C-rich pyrimidine regions and have various important roles in post-transcriptional activities. PCBP4 binds preferentially to single-stranded nucleic acid oligo- dC. Localized to the cytoplasm, PCBP4 contains 4 KH domains, which are RNA binding sites. The gene that encodes PCBP4 is induced by the p53 tumor suppressor and PCBP4 has been shown to induce apoptosis and cell cycle arrest in G(2)-M. PCBP4 is expressed as two isoforms produced by alternative splicing.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of PCBP4 of mouse rat and human origin by WB IP and ELISA also reactive with additional species including canine
Tissue Specificity
recommended for detection of PCBP4 of mouse, rat and human origin by WB, IP and ELISA; also reactive with additional species, including canine