Application
Western blot analysis of Mucin 3B expression in Jurkat whole cell lysate.| Product Name | Mucin 3B Antibody (S-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against Mucin 3B of human origin |
| Modification Notes | The Mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3A and Mucin 3B). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3A and Mucin 3B are major components of various mucus gels and, while Mucin 3A is broadly expressed in normal and tumor cells, Mucin 3B is predominantly expressed in adult and fetal small intestine and colon. Mucin 3B is a major component of mucus gels and is thought to provide protective lubrication against infectious particles at mucosal surfaces. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of Mucin 3B of human origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against Mucin 3B of human origin |
|---|---|
| Tissue Specificity | raised against Mucin 3B of human origin |
Application
Western blot analysis of Mucin 3B expression in Jurkat whole cell lysate.| Application Notes | recommended for detection of Mucin 3B of human origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
