Application
Western blot analysis of UBL4A expression in non-transfected (A) and human UBL4A transfected (B) 293 whole cell lysatesApplication
Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.| Product Name | UBL4A Antibody (C-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of UBL4A of human origin by IF, IHC(P) and ELISA |
| Modification Notes | The distal portion of the long arm of the human X chromosome is one of the most gene dense portions in the entire human genome and also contains many genes that have been linked to genetic diseases. The gene encoding the 157 amino acid protein, UBL4A (Ubiquitin-like protein 4A), has a CpG island in the 5' region and is located on the X chromosome in close proximity to the gene encoding G6PD. UBL4A, also known as GDX, has been characterized as a ubiquitously expressed and highly conserved protein from humans to plants. The N-terminal region of UBL4A shares 43% sequence identity with ubiquitin, however the C-terminal region has no homology to ubiquitin and it is therefore unlikely that UBL4A plays any role in targeting cellular proteins for degradation. Due to gene promoter features, such as being rich in G-C residues, lacking TATA boxes and the repetition of the Sp1 transcription factor binding site, it is likely that the gene encoding UBL4A functions as a housekeeping gene. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IFIHCELISA |
| IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of UBL4A of human origin by IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of UBL4A of human origin by IF, IHC(P) and ELISA |
| Entrez Gene | 8266 |
|---|
Application
Western blot analysis of UBL4A expression in non-transfected (A) and human UBL4A transfected (B) 293 whole cell lysates
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.| Application Notes | IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
