| Product Name | LINE-1 Antibody (H-110) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1081-1190 mapping near the C-terminus of LINE-1 of human origin |
| Modification Notes | Mammalian LINE-1 (L1) elements belong to the superfamily of autonomously replicating retrotransposable elements that lack the long terminal repeated (LTR) sequences typical of retroviruses and retroviral-like retrotransposons. The non-LTR superfamily is ubiquitous in nature and constitutes 20% or more of some mammalian genomes, and about 5% of the human genome. Therefore, Line-1 elements presumably have had a profound, perhaps defining, effect on the evolution, structure and function of mammalian genomes. Line-1 elements contain regulatory signals and encode two proteins: an RNA-binding protein and an integrase-replicase, as the retrovirus harbors both endonuclease and reverse transcriptase capabilities. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LINE-1 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1081-1190 mapping near the C-terminus of LINE-1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1081-1190 mapping near the C-terminus of LINE-1 of human origin |
| Application Notes | recommended for detection of LINE-1 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
