| Product Name | FBXO27 Antibody (K-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of FBXO27 of human origin |
| Modification Notes | In eukaryotes, degradation of damaged or excess proteins into short peptides is carried out by proteasomes. The proteasomes bind polyubiquitin chains that are added to the target proteins through a phosphorylation-dependent reaction catalyzed by ubiquitin ligases, such as the SCF-type E3 complex containing Skp, Cullin, Rbx1 and F-box proteins. F-box proteins, such as FBXO27 (F-box only protein 27), possess structural motifs used for directly aggregating the substrate while binding to the Skp1 bridge providing for close proximity to the functional E2 ubiquitin-conjugating enzyme, Cullin/Rbx1. FBXO27, also known as FBG5 and FBX27, is a 283 amino acid protein that contains an N-terminal F-box and a C-terminal F-box-associated domain. FBXO27 found highly expressed in brain, heart and kidney with lower levels found in kidney and liver. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBELISA |
| recommended for detection of FBXO27 of human origin by WB and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of FBXO27 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of FBXO27 of human origin |
| Entrez Gene | 126433 |
|---|
| Application Notes | recommended for detection of FBXO27 of human origin by WB and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
