Application
Western blot analysis of JK-1 expression in non-transfected: (A) and human JK-1 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of JK-1 expression in Jurkat whole cell lysate.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human lung tissue showing nuclear and cytoplasmic staining.| Product Name | JK-1 Antibody (Y-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against JK-1 of human origin |
| Modification Notes | Esophageal squamous cell carcinoma (ESCC) is cancer of the flat cells lining the esophagus, and is currently the ninth most frequent cancer in the world. While environmental risk factors, such as alcohol drinking and cigarette smoking, increase chances of ESCC, several genes are believed to be involved in the origin and/or progression of ESCC. The proteins encoded by these genes include p53, DCC, DEC1, DLEC1, p16 and TGF∫ RII. JK-1, also known as FAM134B, is a 497 amino acid multi-pass membrane protein. JK-1 overexpression in ESCC cell lines causes increased cell growth rate, indicating a possible role in ESCC progression. JK-1 is expressed as two isoforms produced by alternative splicing. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of JK-1 of mouse, rat, human and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against JK-1 of human origin |
|---|---|
| Tissue Specificity | raised against JK-1 of human origin |
| Entrez Gene | 54463 |
|---|
Application
Western blot analysis of JK-1 expression in non-transfected: (A) and human JK-1 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of JK-1 expression in Jurkat whole cell lysate.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human lung tissue showing nuclear and cytoplasmic staining.| Application Notes | recommended for detection of JK-1 of mouse, rat, human and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
