Application
Western blot analysis of SAP 30BP expression in non-transfected: (A) and human SAP 30BP transfected: (B) 293T whole cell lysates.Application
Western blot analysis of SAP 30BP expression in fetal muscle tissue extract.| Product Name | SAP 30BP Antibody (S-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against SAP 30BP of human origin |
| Modification Notes | SAP 30BP (SAP 30 binding protein), also known as HTRG, HTRP or HCNGP, is a 308 amino acid protein that belongs to the HCNGP family and is believed to function as a transcription regulator. Expressed in brain, liver, spleen, kidney, lung and heart, SAP 30BP localizes to the nucleus and is induced in fibroblasts by binding of HSV-1 (herpes simplex virus 1). In the nucleus, SAP 30BP interacts with SAP 30, a component of the histone deacetylase complex that also contains mSin3A, HDAC1, HDAC2, RbAp48, RbAp46 and SAP 18. Via this interaction, SAP 30BP is thought to play a role in the regulation of genes related to cell survival. In addition, SAP 30BP is capable of inducing cell death, suggesting that it functions in cellular corepression of transcription and inhibition of cell survival. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of SAP 30BP of mouse, rat, human and canine origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against SAP 30BP of human origin |
|---|---|
| Tissue Specificity | raised against SAP 30BP of human origin |
| Entrez Gene | 29115 |
|---|
Application
Western blot analysis of SAP 30BP expression in non-transfected: (A) and human SAP 30BP transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of SAP 30BP expression in fetal muscle tissue extract.| Application Notes | recommended for detection of SAP 30BP of mouse, rat, human and canine origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
