Application
Western blot analysis of PLP2 expression in Hep G2 whole cell lysate.| Product Name | PLP2 Antibody (Y-18) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against PLP2 of human origin |
| Modification Notes | Proteolipid protein 2, also known as PLP2 or A4, is a 152 amino acid, multi-pass transmembrane protein containing a MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain. Proteins containing the MARVEL domain have an M-shaped topology, with four transmembrane-helix regions and cytoplasmic N- and C-terminal regions. Localized to the membrane, PLP2 is highly enriched in colonic mucosa and is expressed in a gradient along the crypto-villus axis, with the most abundant expression in the lower half of the crypt. PLP2 has been thought to play a role in chemotaxis and cell differentiation in the intestinal epithelium. PLP2 has also been found in the pyramidal cells of hippocampus and granular cells of the cerebellum and has been implicated in X-linked mental retardation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of PLP2 of human and canine origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against PLP2 of human origin |
|---|---|
| Tissue Specificity | raised against PLP2 of human origin |
| Entrez Gene | 5355 |
|---|
Application
Western blot analysis of PLP2 expression in Hep G2 whole cell lysate.| Application Notes | recommended for detection of PLP2 of human and canine origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
