Application
Western blot analysis of DCDC2 expression in mouse brain (A), rat brain (B) and rat kidney (C) tissue extracts.| Product Name | DCDC2 Antibody (M-125) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 351-475 mapping at the C-terminus of DCDC2 of mouse origin |
| Modification Notes | The DCDC2 gene encodes the DCDC2 protein (Doublecortin-containing protein 2, RU2, RU2S) which contains two Doublecortin peptide domains similar to those in the Doublecortin gene. DCDC2 is transcribed as a “normal” gene, which results in a sense transcript (RU2S), but when it is transcribed in the opposite direction, a shorter antisense transcript (RU2AS), which is found in tumors, results. The DCDC2 protein demonstrates ubiquitous expression, whereas RU2AS expression is restricted to normal kidney, bladder, liver and testis, and to tumors of various histologic origins. The deduced DCDC2 protein contains 476 amino acids, while the RU2AS protein contains 84 residues. There is a significant association between dyslexia and several SNPs within the DCDC2 gene. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of DCDC2 mouse isoform 1 of mouse and rat origin by WB, IP, IF and ELISA non cross-reactive with isoform 2: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 351-475 mapping at the C-terminus of DCDC2 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 351-475 mapping at the C-terminus of DCDC2 of mouse origin |
| Entrez Gene | 195208 |
|---|
Application
Western blot analysis of DCDC2 expression in mouse brain (A), rat brain (B) and rat kidney (C) tissue extracts.| Application Notes | recommended for detection of DCDC2 mouse isoform 1 of mouse and rat origin by WB, IP, IF and ELISA non cross-reactive with isoform 2: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
