Application
Indirect FCM analysis of Ramos cells stained with CKR-7 (ELC-Fc), followed by FITC-conjugated rabbit anti-human IgG: . Black line histogram represents the isotype control, normal human IgG.Application
Indirect FCM analysis of Ramos cells stained with CKR-7 (ELC-Fc), followed by PE-conjugated rabbit anti-human IgG: . Black line histogram represents the isotype control, normal human IgG.Application
Indirect FCM analysis of Ramos cells stained with CKR-7 (ELC-Fc), followed by PE-conjugated goat anti-human IgG: . Black line histogram represents the isotype control, normal human IgG.Application
Indirect FCM analysis of Ramos cells stained with CKR-7 (ELC-Fc), followed by FITC-conjugated goat anti-human IgG: . Black line histogram represents the isotype control, normal human IgG.Application
FCM analysis of Ramos cells. Black line histogram represents the isotype control, normal human IgG1.| Product Name | CKR-7 Antibody (ELC-Fc) PCPC5 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | developed by fusing recombinant ELC (CKR-7 ligand) to human IgG1 Fc |
| Modification Notes | C-C or ∫ chemokine family members are characterized by a pair of adjacent cysteine residues and serve as potent chemoattractants and activators of monocytes and T cells. C-C chemokine receptor family members include CKR-1, CKR-2A, CKR-2B, CKR-3, CKR-4, CKR-5, CKR-6, CKR-7, CKR-8, CKR-9, CKR-10 and the Duffy blood group antigen. Each of these receptors are G protein-coupled, seven pass transmembrane domain proteins whose major physiological role is to function in the chemotaxis of T cells and phagocytic cells to areas of inflammation. However, this receptor family has also been shown to facilitate viral infection. CKR-7 (C-C chemokine receptor type 7), also known as CCR7, CMKBR7, EBI1 or EVI1, is a 378 amino acid multi-pass membrane protein that belongs to the CC-chemokine receptor family. Expressed in activated B- and T-lymphocytes, as well as in various lymphoid tissues, CKR-7 functions as a receptor for MIP-3∫ and is thought to be involved in mediating normal lymphocyte function. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IFFC |
| recommended for detection of CKR-7 of mouse and human origin by IF and FCM appropriate control for FCM is normal human IgG1: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | developed by fusing recombinant ELC (CKR-7 ligand) to human IgG1 Fc |
|---|---|
| Tissue Specificity | developed by fusing recombinant ELC (CKR-7 ligand) to human IgG1 Fc |
Application
Indirect FCM analysis of Ramos cells stained with CKR-7 (ELC-Fc), followed by FITC-conjugated rabbit anti-human IgG: . Black line histogram represents the isotype control, normal human IgG.
Application
Indirect FCM analysis of Ramos cells stained with CKR-7 (ELC-Fc), followed by PE-conjugated rabbit anti-human IgG: . Black line histogram represents the isotype control, normal human IgG.
Application
Indirect FCM analysis of Ramos cells stained with CKR-7 (ELC-Fc), followed by PE-conjugated goat anti-human IgG: . Black line histogram represents the isotype control, normal human IgG.
Application
Indirect FCM analysis of Ramos cells stained with CKR-7 (ELC-Fc), followed by FITC-conjugated goat anti-human IgG: . Black line histogram represents the isotype control, normal human IgG.
Application
FCM analysis of Ramos cells. Black line histogram represents the isotype control, normal human IgG1.| Application Notes | recommended for detection of CKR-7 of mouse and human origin by IF and FCM appropriate control for FCM is normal human IgG1: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
