Application
Western blot analysis of group VI iPLA2 expression in 293T whole cell lysate.| Product Name | group VI iPLA2 Antibody (H-120) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against amino acids 1-120 of group VI iPLA2 of human origin |
| Modification Notes | Phospholipases catalyze the release of fatty acids from phospholipids. One member of the phospholipase family, iPLA2, is detected as a membrane-bound protein with multiple smaller isoforms, which result from alternative splicing. Two isoforms, Ankyrin-iPLA2-1 and -2, lack the catalytic domain and are thought to be involved in the negative regulation of iPLA2 activity. The SH-iPLA2 isoform is cytoplasmically localized. The human gene encoding iPLA2 maps to chromosome 22q13.1. Another phopholipase, sPLA2, belongs to a family of secretory phospholipases A2, which represent an expanding family of related enzymes. sPLA2 has both membrane bound and secreted forms that are encoded by a single gene. sPLA2 is involved in the regulation of phospholipid metabolism in biomembranes and in eicosanoid biosynthesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of group VI iPLA2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against amino acids 1-120 of group VI iPLA2 of human origin |
|---|---|
| Tissue Specificity | raised against amino acids 1-120 of group VI iPLA2 of human origin |
| Entrez Gene | 8398 |
|---|
Application
Western blot analysis of group VI iPLA2 expression in 293T whole cell lysate.| Application Notes | recommended for detection of group VI iPLA2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
