Application
Western blot analysis of Integrin αM expression in mouse peripheral blood lysate.Application
Western blot analysis of Integrin αM expression in human PBL whole cell lysate.| Product Name | Integrin αM Antibody (H-61) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1050-1110 mapping within an extracellular domain of Integrin αM of human origin |
| Modification Notes | Integrin åM, also designated complement component receptor-3 å, CD11b (p170), macrophage antigen a polypeptide, cell surface glycoprotein Mac-1 a subunit, MAC1A, MO1A and ITGAM) is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin åM combines with the Integrin ∫2 to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin åM/∫2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Integrin αM of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1050-1110 mapping within an extracellular domain of Integrin &alpha M of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1050-1110 mapping within an extracellular domain of Integrin αM of human origin |
| Entrez Gene | 3684 |
|---|
Application
Western blot analysis of Integrin αM expression in mouse peripheral blood lysate.
Application
Western blot analysis of Integrin αM expression in human PBL whole cell lysate.| Application Notes | recommended for detection of Integrin αM of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
