epitope mapping within an internal region of GLT8D3 of human origin
Modification Notes
GLT8D3 (glycosyltransferase 8 domain-containing protein 3), also known as GXYLT1 (glucoside xylosyltransferase 1), is a 440 amino acid single-pass type II membrane protein. Belonging to the glycosyltransferase 8 family, GLT8D3 is a xylosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose. GLT8D3 contains a short N-terminal cytoplasmic domain, followed by a transmembrane domain, a stem region and a large glycosyltransferase domain containing the conserved DxD motif. GLT8D3 exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 12q12 and mouse chromosome 15 E3.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of GLT8D3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with GLT8D1, GLT8D2 or GLT8D4 also reactive with additional species, including equine, canine and bovine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of GLT8D3 of human origin
Tissue Specificity
epitope mapping within an internal region of GLT8D3 of human origin
Western blot analysis of GLT8D3 expression in non-transfected: (A) and human GLT8D3 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of GLT8D3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with GLT8D1, GLT8D2 or GLT8D4 also reactive with additional species, including equine, canine and bovine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.