epitope mapping near the C-terminus of GLT8D3 of human origin
Modification Notes
GLT8D3 (glycosyltransferase 8 domain-containing protein 3), also known as GXYLT1 (glucoside xylosyltransferase 1), is a 440 amino acid single-pass type II membrane protein. Belonging to the glycosyltransferase 8 family, GLT8D3 is a xylosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose. GLT8D3 contains a short N-terminal cytoplasmic domain, followed by a transmembrane domain, a stem region and a large glycosyltransferase domain containing the conserved DxD motif. GLT8D3 exists as two alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 12q12 and mouse chromosome 15 E3.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of GLT8D3 of human origin by WB, IP, IF and ELISA non cross-reactive with GLT8D1, GLT8D2 or GLT8D4:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping near the C-terminus of GLT8D3 of human origin
Tissue Specificity
epitope mapping near the C-terminus of GLT8D3 of human origin