| Product Name | ADAM6 Antibody (M-145) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 511-655 mapping near the C-terminus of ADAM6A of mouse origin |
| Modification Notes | ADAMs (disintegrin and metalloproteinase domain), also known as MDCs (metalloproteinase, disintegrin, and cysteine-rich domain) or cellular disintegrins are a family of proteins that are ubiquitously expressed. They catalyze proteolysis, adhesion, fusion and intracellular signaling. ADAMs are membrane-anchored, glycosylated, Zn2+ dependent proteases, and there are over 30 different members in the family with many diverse functions. ADAMs 1-6 localize to the testis and are developmentally regulated. ADAMs 1-6 are involved in spermatogenesis and sperm-egg binding and fusion. ADAM6 is exclusively expressed in the germ cells of the testis. Evidence has shown that peptides targeting the disintegrin domain of ADAM6 do not disturb spermatogenic cell attachment to Sertoli cell surfaces. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ADAM6A and ADAM6B of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 511-655 mapping near the C-terminus of ADAM6A of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 511-655 mapping near the C-terminus of ADAM6A of mouse origin |
| Entrez Gene | 238406 |
|---|
| Application Notes | recommended for detection of ADAM6A and ADAM6B of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
