Application
Western blot analysis of SOCS-6 expression in non-transfected 293T: (A), mouse SOCS-6 transfected 293T: (B), BJAB (C) and Ramos (D) whole cell lysates.Application
Western blot analysis of SOCS-6 expression in non-transfected 293T: (A), mouse SOCS-6 transfected 293T: (B), BJAB (C) and Ramos (D) whole cell lysates.Application
Western blot analysis of SOCS-6 expression in non-transfected CHO: (A), human SOCS-6 transfected CHO: (B) and BJAB (C) whole cell lysates.Application
Western blot analysis of SOCS-6 expression in BJAB whole cell lysate.Application
Western blot analysis of SOCS-6 expression in non-transfected (A) and human SOCS-6 transfected (B) CHO whole cell lysates.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic and membrane staining of cells in glomeruili and tubuli at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Western blot analysis of SOCS-6 expression in TNFα-treated NIH/3T3 whole cell lysate.| Product Name | SOCS-6 Antibody (H-251) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 132-382 mapping to an internal region of SOCS-6 of human origin |
| Modification Notes | The SOCS (suppressor of cytokine signaling) gene family consists of a group of proteins that negatively regulate cytokine signal transduction. The SOCS family proteins contain a central SH2 domain and a carboxy-terminal region termed the “SOCS box.” The SOCS-1 (also called SSI-1 and JAB), SOCS-2 (also called SSI-2 and CIS2) and SOC-3 (also called SSI-3 and CIS3) genes are known to be upregulated by IL-6 and other cytokines. SOCS-4, SOCS-5, SOCS-6 and SOCS-7 were identified by their sequence homology with the SOCS box. CIS (for cytokine-inducible SH2-containing protein) is also a member of the SOCS family. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of SOCS-6 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 132-382 mapping to an internal region of SOCS-6 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 132-382 mapping to an internal region of SOCS-6 of human origin |
| Entrez Gene | 9306 |
|---|
Application
Western blot analysis of SOCS-6 expression in non-transfected 293T: (A), mouse SOCS-6 transfected 293T: (B), BJAB (C) and Ramos (D) whole cell lysates.
Application
Western blot analysis of SOCS-6 expression in non-transfected 293T: (A), mouse SOCS-6 transfected 293T: (B), BJAB (C) and Ramos (D) whole cell lysates.
Application
Western blot analysis of SOCS-6 expression in non-transfected CHO: (A), human SOCS-6 transfected CHO: (B) and BJAB (C) whole cell lysates.
Application
Western blot analysis of SOCS-6 expression in BJAB whole cell lysate.
Application
Western blot analysis of SOCS-6 expression in non-transfected (A) and human SOCS-6 transfected (B) CHO whole cell lysates.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic and membrane staining of cells in glomeruili and tubuli at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Western blot analysis of SOCS-6 expression in TNFα-treated NIH/3T3 whole cell lysate.| Application Notes | recommended for detection of SOCS-6 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
