Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human rectum tissue showing cytoplasmic and nuclear staining of glandular cells.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic and nuclear staining of cells in tubules.Application
Western blot analysis of L-FABP expression in mouse liver tissue extract (A) and Hep G2 whole cell lysate (B).Application
Western blot analysis of L-FABP expression in non-transfected 293T: (A), mouse L-FABP transfected 293T: (B) and Hep G2 (C) whole cell lysates.Application
Western blot analysis of L-FABP expression in Hep G2 whole cell lysate.| Product Name | L-FABP Antibody (H-120) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 7-126 mapping within an internal region of L-FABP of human origin |
| Modification Notes | Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). Liver-specific FABP (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors and is required for cholesterol synthesis and metabolism. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of L-FABP of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 7-126 mapping within an internal region of L-FABP of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 7-126 mapping within an internal region of L-FABP of human origin |
| Entrez Gene | 2168 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human rectum tissue showing cytoplasmic and nuclear staining of glandular cells.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic and nuclear staining of cells in tubules.
Application
Western blot analysis of L-FABP expression in mouse liver tissue extract (A) and Hep G2 whole cell lysate (B).
Application
Western blot analysis of L-FABP expression in non-transfected 293T: (A), mouse L-FABP transfected 293T: (B) and Hep G2 (C) whole cell lysates.
Application
Western blot analysis of L-FABP expression in Hep G2 whole cell lysate.| Application Notes | recommended for detection of L-FABP of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
