Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human oral mucosa tissue showing cytoplasmic staining of squamous epithelial cells.Application
Western blot analysis of CaMKKβ expression in rat cerebellum (A) and mouse brain (B) tissue extracts.| Product Name | CaMKKβ Antibody (H-95) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-95 mapping at the N-terminus of CaMKKβ of human origin |
| Modification Notes | The Ca2+/calmodulin-dependent protein kinases (CaM kinases) are a structurally related subfamily of Serine/Threonine kinases that includes CaMKI, CaMKII and CaMKIV (1-4). CaMKI and CaMKIV are stimulated by Ca2+ and CaM, but phosphorylation by a CaMK is also required for full activation (1,5). CaMKKå and CAMKK∫ function to activate CaMKI through the specific phosphorylation of the regulatory threonine residue at position 177. CAMKK∫ is also capable of phosphorylating CAMKIV on Threonine residue 200 (6,7). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of CaMKKβ of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-95 mapping at the N-terminus of CaMKK&beta of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-95 mapping at the N-terminus of CaMKKβ of human origin |
| Entrez Gene | 10645 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human oral mucosa tissue showing cytoplasmic staining of squamous epithelial cells.
Application
Western blot analysis of CaMKKβ expression in rat cerebellum (A) and mouse brain (B) tissue extracts.| Application Notes | recommended for detection of CaMKKβ of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
